子宫内膜癌合并高血压病、糖尿病的临床分析

A Clinical Analysis of Endometrial Cancer Accompanied by Hypertension and Diabetes Mellitus

目的:探讨子宫内膜癌患者合并高血压病、糖尿病等合并症对其临床病理特征、治疗和预后的影响。方法:对1990年1月～2000年7月在我院住院治疗并有完整资料的234例子宫内膜癌患者进行对比分析,其中合并症组48例。无合并症组186例。结果:合并症组患者平均年龄56.56岁.对照组患者平均年龄51.76岁,两组比较差异有显著性(P<0.05);合并症的发生与肿瘤临床分期、病理类型、分化程度和是否接受手术无关(P>0.1);但合并症组中接受辅助治疗的比例(85.42%)明显高于对照组(69.89%))(P<0.05)。对随访的患者进行单因素分析显示:合并症与子宫内膜癌预后无关(P>0.1)。结论:子宫内膜癌合并高血压病、糖尿病的机率随年龄增大而增加,但合并症的发生与其临床病理特征和是否接受手术无关,虽然接受辅助治疗的比例增加,但对预后无明显影响。

Objective： To investigate the influence of the complications of hypertension and diabetes mellitus on the clinical pathological characteristics, treatment and prognosis of endometrial cancer. Methods： The complete data of 234 patients with endometrial cancer who were hospitalized in our hospital from January 1990 to July 2000 were compared and analyzed, in- cluding complication group （ n = 48 ） and without complication group （ n = 186 ）. Results： The mean age was 56.56 years in the complication group, but 51.76 years in the without complication group, and there was significant difference between the two groups （P 〈 0.05 ）. The occurrence of complications had no correlation with the clinical stage, pathological type, severity of differentiation and accept surgery or not （P 〉 0.05 ）. The proportion of accepting assistant therapy in the complication group （85.24%） was obviously higher than that in the without complication group （69.89%） （P 〈0. 05 ）. The univariate analysis showed that complications had no correlation with the prognosis of endometrial cancer （P 〉 0. 1 ）. Conclusion： The probability of complications of hypertension and diabetes mellitus in endometrial cancer is increased as aging, but the occurrence of complications has no association with the clinical pathological characteristics and accept surgery or not. The proportion of accepting assistant therapy is increased, but it has no obvious influence on the prognosis.