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冻融胚胎移植69例临床分析 被引量：1

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摘要 目的探讨冻融胚胎移植的临床应用,提高体外受精-胚胎移植累积妊娠率。方法采用慢速冷冻、快速解冻的方法对69个体外受精-胚胎移植周期的剩余胚胎进行冷冻复苏。分为2组,其中一组进行激光辅助孵化。对比2组移植情况。结果在69个冷冻复苏周期中,共复苏281个胚胎,成活171个胚胎,复苏率60.9%;复苏后移植66个周期,临床妊娠率27.3%(18/66),种植率16.0%(24/150)。激光辅助孵化组妊娠率35.5%(11/31),种植率20.5%(15/73);对照组(未行激光辅助孵化)妊娠率20.0%(7/35),种植率11.7%(9/77)。目前已分娩14个健康新生儿,1例流产,另有5例在妊娠随访中。结论冻融胚胎移植提高了体外受精-胚胎移植单次取卵周期的累积妊娠率,激光辅助孵化可以改善冻融胚胎移植的妊娠率和种植率。
作者 黄晓洁 张雪 张荣荣 王伟萍 程婷婷
机构地区 徐州市妇幼保健院生殖医学中心
出处 《徐州医学院学报》 CAS 2007年第10期661-663,共3页 Acta Academiae Medicinae Xuzhou
关键词 不孕症 女性 胚胎移植 冻融胚胎
分类号 R771.6 [医药卫生—眼科]
  • 相关文献

参考文献7

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二级参考文献11

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共引文献12

同被引文献5

  • 1Kuwayama M. Highly efficient vitrification for cryopreservation of human oocytes and embryos: the Cryotop method[J]. Theriogenology, 2007, 67(1):73-80.
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  • 3Kuwayama M, Vajta G, Ieda S, et al. Comparison of open and closed methods for vitrification of human embryos and the elimination of potential contamination [J]. Reprod Biomed Online, 2005,11(5) :608-614.
  • 4Mojtaba Rezazadeh Valojerdi, Poopak Eftekhari Yazdi, and Leila Karimian, et al. Vitrification versus slow freezing gives excellent survival, post warming embryo morphology and pregnancy outcomes for human cleaved embryos[J]. J Assist Reprod Genet, 2009, 26(6) :347-354.
  • 5Balaban B, Urman B, Ata B, et al. A randomized controlled study of human day 3 embryo cryopreservation by slow freezing or vitrification: vitrification is associated with higher survival, metabolism and blastocyst formation[J]. Hum Reprod, 2008, 23 (9):1976-1982.

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徐州医学院学报
2007年 第10期

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