期刊文献+

吉西他滨联合草酸铂治疗晚期肝癌 被引量:3

Gemcitabine plus oxaliplatin for patients with advanced hepatocellular carcinoma
下载PDF
导出
摘要 目的探讨晚期肝癌的合适的化疗方案。方法采用吉西他滨联合草酸铂方案对10例晚期肝癌患者进行治疗。结果2例有效。本方案毒性反应轻微,以血小板减少为主。结论吉西他宾联合草酸铂化疗方案效果较好。 Objective To study the chemotherapy for advanced hepatocellular carcinoma. Methods Ten patients were treated by using gemcitabine plus oxaliplatin. Results The regime was found to be effective in 2 of the 10 cases. The toxicity was mild, mostly appeared as thrombocytopenia. Conclusion Gemcitabine - oxaliplatin combination therapy is a promising one for treating advanced hepatocellular carcinoma.
出处 《徐州医学院学报》 CAS 2007年第10期685-687,共3页 Acta Academiae Medicinae Xuzhou
关键词 肝癌 化学疗法 吉西他滨 草酸铂 hepatocellular carcinoma chemotherapy gemcitabine oxaliplatin
  • 相关文献

参考文献6

  • 1Taieb J, Bonyhay L, Golli L, et al. Gemcitabine plus oxaliplatin for patients with advanced hepatocellular carcinoma using two different schedules [J]. Cancer, 2003,98(12):2664-2669.
  • 2Lai CL, Wu PC, Chan GC, et al. Doxorubicin Versus no antitumor therapy in inoperable hepatocellular carcinoma. A prospective randomized trial [J]. Cancer,1988,62(3) :479-483.
  • 3Chao Y, Chan WK, Birkhofer MJ, et al. Phase Ⅱ and pharmacokinetic study of paclitaxel therapy for unresectable hepatocellular carcinoma patients [ J ]. Br J Cancer, 1998,78 ( 1 ) :34 - 39.
  • 4Yang TS, Wang CH, Hsieh RK, et al. Gemeitabine and doxorubicin for the treatment of patients with advanced hepatocellular carcinoma: a phase Ⅰ-Ⅱ trial [J]. Ann Oncol, 2002,13(11) :1771 - 1778.
  • 5Koren G, Beatty K, Seto A, et al. The effects of impaired liver function on the elimination of antineoplastic agents [ J ]. Ann Pharmacother, 1992,26 (3) :363 - 371.
  • 6Donelli MG, Zucchetti M, Munzone E, et al. Pharmacokinetics of anticancer agents in patients with impaird liver fuction [ J]. Eur J Cancer, 1998,34 ( 1 ) :33 - 46.

同被引文献134

引证文献3

二级引证文献61

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部