成人麻疹67例临床分析

The analysis of epidemioiogical and clinical characteristics of 67 clinical cases of adult-measles

目的探讨成人麻疹的流行特征及临床特征。方法对67例麻疹患者的临床资料进行回顾性分析。结果67例患者(男39例,女28例),男女比为1.39:1,平均年龄32.1岁,发病季节4～6月份多发(40.3%),发病高峰年在2000年11月至2004年10月(67.2%)。检测的血清麻疹IgM抗体阳性率为95.1%(39/41),热峰高于39℃58例(86.6%),并发麻疹病毒性肝炎18例(26.9%)。结论成人麻疹流行特征可能与麻疹疫苗接种不规范或体内抗体滴度下降等因素有关,临床特征为具有较重的病毒血症以及肝脏损害等。

Objective To evaluate the epidemiological and clinical characteristics of adult-measles. Methods The clinical data of 67 patients with adult-measles were retrospectively analyzed. Results In summary, 67 patients with measles were involved in this study,with 39 males and 28 females. The gender rate was 1.39：1 and the average age was about 32 years old. There were 39 peasants and 28 workers ＆ officials of 67 patients. The peak of the incidence of disease emerged in April and June（40.3% ）, especially from November 2000 to October 2004 （67.2 96 ）, and the positive rate of measles virus IgM antibody in serum was 95.1% （39/41）. There were 58 patients （86.6%-） who had the fever beyond 39Z] and 18 patients（26.9% ） who had measles induced viral hepatitis. Conclusions There is a trend that measles may be related to the nonstandard inoculation of measles vaccine of the decrease of IgM antibody levels and so on. Meanwhile, serious toxemic symptoms and liver damage can be clinically observed.