高聚金葡素胸腔内注射对结核性胸腔积液的疗效观察

Clinical Effects of Injecting Highly Agglutinated Staphylococcin on Pleural Effusion Induced by Tuberculosis

目的：观察结核性胸腔积液注射高聚金葡素的疗效。方法：结核性胸膜炎患者46例随机分为2组,治疗组26例,对照组20例。治疗组采用正规抗结核同时抽胸水,2次/周,胸腔内注射高聚金葡素针2000U。对照组采用正规抗结核同时抽胸水,2次/周。结果：经10～19d治疗,治疗组患者胸水吸收较快,胸水消失时间与对照组相比差异有显著意义（P〈0.005）。结论：胸腔内注射高聚金葡素治疗结核性胸膜炎不良反应较少而轻微,对症治疗能缓解,是有效、安全的辅助治疗方法之一。

Objective： To explore clinical effects of injecting highly agglutinated staphylococcin （HAS） on pleural effusion induced by tuberculosis. Methods： 46 patients with tuberculosis pleurisy were randomly divided into two groups. 26 patients in one group were treated with antituberculotic therapy regular and thoracentesis, combining with injecting highly agglutinated staphylococcin（HAS） into thoracic cavity at a dose of 2 000 U, while the 20 patients on the contrary group were not treated with HAS. Results： After 10 - 19 days therapy, the pleural effusion of the treatment group was disappeared much fast than the contrary group. There is great difference between the two groups（ P 〈 0. 005 ） about the time of hydrothorax disappearing. And there is no adverse effect. Conclusions： Conclusion Injecting HAS into thoracic cavity is a safe and effective auxiliary way to treat pleural effusion induced by tuberculosis