摘要
目的:评价18F-脱氧葡萄糖(18F-FDG)PET/CT显像、CT在乳腺癌术后复发和转移诊断中的应用价值。方法:37例临床疑乳腺癌术后复发的患者行18F-FDG PET/CT全身显像。图像分析采用视觉和半定量方法(标准摄取值,SUV)分析肿瘤病灶摄取FDG的程度,并参考近期病理检查及CT结果。结果:27例复发患者经组织病理学、活检或细胞学检查和临床随访证实有局部转移,PET/CT显像和CT检查灵敏度分别为96.30%,62.96%,PET/CT显像和CT检查的灵敏度的差异有显著性(χ2=9.247,P<0.05)。14例患者行PET/CT双时相检查,乳腺癌术后患者确诊为转移的9例患者,SUV值均有不同程度增高。结论:18F-FDG PET/CT显像对于乳腺癌术后复发和转移病灶的定性、定位准确性更高,优于CT,是一种有效的诊断方法。
Objective： To evaluate the use of ^18F-fluorodeoxyglucose （FDG） PET/CT in recurrence and metastasis of breast cancer. Methods： Thirty-seven patients after operation underwent ^18F-FDG PET/CT whole body imaging for evaluation of recurrent breast cancer and metastasis. Visual and semiquantitative methods （standard uptake value, SUV） were used to analyze the images. The results of PET/CT imaging were compared with those of pathology or CT. Results： Twenty-seven malignant recurrent breast lesions in thirty-seven resected breast cancers detected by this modality were proven histopathology, biopsy, cytological examination, and clinical follow-up. Among the twenty-seven malignant breast lesions, the diagnostic sensitivity of PET/CT and CT imaging were 96.30% and 62.96% respectively. There were statistical differences in sensitivity between PET/ CT and CT （χ^2=9.247, P〈0.05）. Fourteen patients with breast cancer underwent PET/CT at 2 time points. Recurrence and metastasis were diagnosed in 9 patients, and all of their SUVs increased at time 2. Conclusions： ^18F-FDG PET/CT makes the location and characterization of the lesions more accurate, and it is a useful diagnostic modality in the diagnosis of recurrent and metastatic breast cancer.
出处
《中国临床医学影像杂志》
CAS
北大核心
2007年第10期689-692,共4页
Journal of China Clinic Medical Imaging
