期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

3-丙烯酰胺基苯硼酸的合成与表征 被引量：6

Synthesis and characterization of 3-acrylamidophenylboronic acid
下载PDF
导出
摘要 3-丙烯酰胺基苯确酸(AAPBA)是合成葡萄糖敏感性水凝胶的关键单体。笔者以3-氨基苯硼酸(APBA)和丙烯酸(AA)为起始原料,1-(3-二甲氨基丙基)-3-乙基碳化二亚胺盐酸盐(EDCI)为缩合剂,通过羧基(—COOH)和氨基(—NH_2)之间的缩合反应合成AAPBA。产物重结晶纯化后经元素分析、红外吸收光谱、核磁共振氢谱、紫外吸收光谱、质谱表征,确证为AAPBA。 3-acrylamidophenylboronic acid （AAPBA） is the key monomer for the synthesis of glucose-sensitive hydrogels. AAPBA was synthesized by the condensation reaction between carboxyl acid group （--COOH） and amino group, based on 3-aminophenylboronic acid （APBA） and acrylic acid （AA） as starting materials and N-Ethyl-N＇-（3-dimethylaminopropyl）carbodiimide hydrochloride （EDCI） as condensating agent. The product purified by recrystallization was verified by elemental analysis, IR, ^1H NMR, UV, MS.
作者 刘紫微 李兰 赵辉鹏 杨明 钱和生 刘晓云 查刘生
机构地区 东华大学分析测试中心
出处 《合成技术及应用》 2007年第3期13-16,共4页 Synthetic Technology & Application
关键词 3-丙烯酰胺基苯硼酸 3-氨基苯硼酸 合成 表征 3-acrylamidophenylboronic acid 3-aminophenylboronic acid condensation reaction characterization
分类号 O627.8 [理学—有机化学]
  • 相关文献

参考文献7

  • 1Takashi Miyata, Tadashi Uragami, Katsuhiko Nakamae. Biomolecule-sensitive hydrogels[J]. Advanced drug delivery reviews, 2002, 54:79 - 98
  • 2Seong II Kang, You Han Bae. A sulfonamide based glucose-responsive hydrogel with covahntly immobilized glucose oxidase and catalase [J]. Journal of Controlled Release, 2003, 86:115 - 121
  • 3Jung Ju Kim, Kinam Park. Modulated Insulin delivery from glucose-sensitive hydrogel dosage forms[J]. Journal of Controlled Release , 2001,77: 39 - 47
  • 4Ve'ronique Lapeyre, Isabelle Gosse, Sylviane Chevreux, Vale'rie Ravaine. Monodispersed Glucose-Responsive Microgels Operating at Physiological Salinity[J]. Biomacromolecules, 2006,7 : 3356 - 3363
  • 5常建华，董绮功．波谱原理及勰析[M]．北京：科学出版社,2001．139
  • 6Daijiro Shiino, Yoshishige Murata, Kazunori Kataoka, Yoshiyuki Koyama, Masayuki Yokoyama . Teruo Okanob and Yasuhisa Sakurais [ J]. Preparation and characterization of a glucose-responsive insulin-releasing polymer device.Biomaterials, 1994,15:121 - 128
  • 7Shigeru Kitano, Issei Hisamitsu, Yoshiyuki Koyama , Kazunori Kataoka.Effect of the incorporation of amino groups in a glucose-responsive polymer complex having phenylborenic acid moieties [ J]. Polymers for Advanced Technologies, 1991,2:261 - 264

同被引文献43

  • 1许媛媛,边超,陈绍凤,夏善红.基于MEMS和A蛋白自组装膜抗体定向固定技术的安培型免疫传感器[J].中国科学（E辑）,2006,36(2):210-221. 被引量：4
  • 2潘和平,陈正英.多肽固相合成缩合试剂──HBTU合成方法的改进[J].化学试剂,1996,18(6):362-363. 被引量：2
  • 3Chalagalla S,Sun XL. Synthesis and characterization of biotin chain-end functionalized boronic acid-containing polymer (boropolymer)as functional glyco-affmity macroligand[J].Reactive and Functional Polymers,2010.471-476.
  • 4Lindberg SE,Wallschlager D,Prestbo FM. Methylated mercury species in municipal waste landfill gas sampled in Florida[J].Atmospheric Environment USA,2001,(23):4011-4015.
  • 5Mallavarapu A,Sawinn K,Mitchison TA. Switch in microtubule dynamics at the onset of anaphase B in the mitotic spindle of Schizosaccharomyces pombe[J].Current Biology,1999,(23):1423-1428.
  • 6Imjun S,Wook Lee J,Sakamoto S. Rotaxane-based molecular switch with fluorescence signaling Switch in microtubule dynamics at the onset of anaphase B in the mitotic spindle of Schizosaccharomyces[J].Tetrahedron Letters,2000,(04):471-475.doi:10.1016/S0040-4039(99)02094-8.
  • 7Shen WW,Ma CN,Wang SF. SnO2@Poly (HEMA-co-St-co-VPBA) core-shell nanoparticles designed for selectively enriching glycopeptides followed by MALDI-MS[J].Analysis Chem Asian J,2010.1185-1191.
  • 8Roy D,Jennifer N. Triply-responsive boronic acid block copolymers:solution self-assembly induced by changes in temperature,pH,or sugar concentrationw[J].Chemical Communications,2009.2106-2108.
  • 9Winson MJ Ma,Marta P,Morais P. Dye displacement assay for saccharide detection with boronate hydrogels[J].Chemical Communications,2009.532-534.
  • 10Ammirati M J,Andrews K M,Boyer D D,et al.(3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-ylpiperazin-1-yl)-pyrrolidin-2-yl]-methanone:A potent,selective,orally active dipeptidyl peptidase IV inhibitor[J].Bioorganic&Medicinal Chemistry Letters,2009,19:1991-1995.

引证文献6

二级引证文献2

合成技术及应用
2007年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部