乙型病毒性肝炎患者血清补体C3、补体C4的临床意义

Serum C3、C4 levels in patients with hepatitis B

目的探讨乙型病毒性肝炎(简称乙肝)患者血清补体C3(C3)、补体C4(C4)的临床意义。方法检测59例乙肝患者的血清C3、C4浓度,据病情分成三组,与对照组进行组间比较。结果除急性肝炎组C4与对照组无显著差异外,其他病例组C3、C4浓度均较对照组明显下降,以重型肝炎最为明显。结论提示C3、C4的检测对乙肝患者病情评估和预后判断有重要意义。

Objective To evaluate the serum C3,CA levels in patients with hepatitis B. Methods 59 cases with hepatitis B were reviewed, their serum C3 ,CA levels were measured. They were divided into different group according to pathogenetic condition. Their serum C3 ,C4 levels were compared with control group and with each others. Among 59 cases, They were divided into 3 group：group A（acute hepatitis B） contained 17 cases, group B （chronic hepatitis B） contained 30 ca- ses, group C （serious hepatitis B） contained 12 cases. Group D （control group） contained 16 eases. Results There was no different in serum CA levels in group A and group D（ P 〈 0. 05 ） , others were significant different in both serum C3 and CA（ P 〈 0. 05 ）. The extent of serum C3 and CA descend was correlated to degree of hepatic injury and immunologic function. Conclusion Serum C3 and C4 levels were important indexes to evaluate the liver function of patients with hepatitis B. It was close correlated to pathogenetic condition.