上海宝山地区人群糖尿病调查及其危险因素分析

Investigation of prevalence and related risk factors of diabetes mellitus in Baoshan district of Shanghai

目的调查上海宝山地区40岁以上人群糖尿病的发病情况并分析其危险因素。方法社区征集2 997例样本,分别进行问卷调查、体格检查和生化检测。χ2检验分析糖尿病可能的危险因素在患病组与正常组间的差异;多因素非条件Logistic回归分析建立危险因素方程。结果上海宝山地区40岁以上人群糖尿病患病率男性为7.3%,女性为6.7%,且患病率随年龄增长而增高(P<0.05)。高龄、腹型肥胖、高血压、高脂血症和糖尿病家族史均被列入Logistic回归模型。对于女性,产巨大胎儿史被列入女性分组中的Logistic回归模型。结论本组资料调查提示,糖尿病患病率在中老年人群中较高,且男性高于女性。高龄、腹型肥胖、高血压、高脂血症、糖尿病家族史和产巨大胎儿史为糖尿病患病的独立危险因素。

Objective To investigate the prevalence and related risk factors of diabetes mellitus in a population older than 40 years in Baoshan District of Shanghai. Methods Two thousand nine hundred and ninety-seven subjects were recruited, and questionnaire, physical and biochemical examinations were administered. Chi- square analysis was used to test the difference of frequency of all risk factors in with-disease group and without-disease group. Multivariate Logistic regression analysis was performed to estimate the odd ratios of all risk factors. Results The prevalence of diabetes mellitus in this population was 7.3% for male and 6.7% for female, and older subjects were more susceptible to the disease（ P 〈 0.05）. Ageing, visceral obesity, hypertension, hyperlipemia and family history of type 2 diabetes mellitus were all included into the Logistic regression model. For female, the history of fetal macrosomia was also included. Conclusion The prevalence of diabetes mellitus in middle-aged and senile population is relatively higher than general ones, and is higher in the male than the female group. Ageing, visceral obesity, hypertension, hyperlipemia, family history of type 2 diabetes mellitus and history of fetal macrosomia are independent risk factors for diabetes mellitus.