摘要
[目的]优选复方益肾软胶囊的最佳提取工艺。[方法]采用正交设计法,以马钱素的提取转移率为评价指标,对乙醇浓度、用量及渗漉速度等影响因素进行研究。[结果]最佳提取工艺为A3B3C1,即用70%乙醇进行渗漉,滴速为3.0mL/(min·kg),收集药材量8倍体积的渗漉液。[结论]本方法优选得到的工艺稳定可行。
[Objective] To explore the optimum extracting conditions for compound Yishen（tonifying the kidney） soft capsule. [Methods] The orthogonal design was taken for the optimization of ethyl alcohol and percolate speed with the content of loganin determined by RP-HPLC. [Results] The optimum extracting conditions were A3B3C1, that is percolating with 70% EtoH, the percolate speed with 3.0 mL/（min·kg）, collecting the amount of percolate 8 times. [Conclusions] The optimum extracting procedure is reasonable and stable.
出处
《天津中医药》
CAS
2007年第5期416-418,共3页
Tianjin Journal of Traditional Chinese Medicine
基金
天津市科技发展计划项目(033187511)。
关键词
复方益肾软胶囊
提取工艺
正交实验
马钱素
compound Yishen soft capsule
extracting conditions
orthogonal test
loganin
