高值血糖对快速血糖仪测定结果影响的系统评价

Systemic evaluation of high level of blood sugar on determined result with high-speed instrument of blood sugar

[目的]评价高值血糖对快速血糖仪测定结果的影响。[方法]计算机检索中国知网数据库和维普数据库,检索年限为1997—2007年。纳入研究高值血糖(>7.8mmol/L)对快速血糖仪测定结果的影响的临床随机对照试验(RCT)和非随机对照研究(CCT)。由两名评价员独立选择试验和提取资料。并按Cochrane系统评价员手册的4条质量评价标准对纳入文献的方法学质量进行评价,而后应用RevMan4.2.10软件做荟萃分析(Meta)。[结果]Meta分析发现,高值血糖对毛细血管全血糖与静脉血浆糖测定结果的差别有统计学意义[WMD(加权平均差值)=-0.98,(-1.40,-0.55)]。[结论]高值血糖对快速血糖仪与全自动生化分析仪测定血糖的结果之间是有影响的,普遍偏低。

[Objective] To evaluate the effect of high Revel of blood sugar on determined result obtained with high-speed instrument for blood sugar. [Methods] The pertinent articles were searched by internet from 1997 to 2007. The method in the Cochrane Reviewer＇s Handbook 4.2.2 was used to evaluate the quality of the articles and analyze the data in them by using meta analysis method. The selected criteria of literatures was high blood sugar（〉7.8 mmol/L） and belonged to RCT and CCT literature. [Results] The eight CCT literatures were selected and included nine hundreds and thirty-two patients. The selected literature had baseline comparability and the quality of literatures was low. Meta analysis found that there was statistical difference between the determined result of capillary and venous blood sugar （WMD=-0.98, （-1.40, -0.55））. [Conclnsions] The determined result of high-speed blood sugar instrument is lower than that of automatic biochemistry analyzer on high blood sugar according to the evidence of selected literatures.