无创正压通气治疗急性心源性肺水肿疗效评价

Clinical efficacy evaluation of non-invasive positive airway pressure ventilation on acute cardiogenic pulmonary edema

目的评价无创正压通气治疗急性心源性肺水肿的临床疗效及安全性。方法24例急性心源性肺水肿常规治疗30min无效时开始接受无创正压通气治疗,监测及分析治疗前后患者临床症状、HR、RR、SBP、DBP、心功能分级及动脉血气指标的变化。结果22例患者经无创正压通气治疗后临床症状及心功能明显改善,HR、RR减慢(P<0.001),SBP、DBP降低(P<0.001),pH、PaO2、SatO2上升,氧和指数增加(P<0.001)。总有效率为91.67%。结论无创正压通气能迅速改善急性心源性肺水肿的临床症状、体征及动脉血气指标,使用安全,是临床救治急性心源性肺水肿的可靠方法。

Objective To evaluate the clinical efficacy of non-invasive positive airway pressure ventilation （NIPPV） on acute cardiogenic pulmonary edema （ACPE）. Methods 24 patients with ACPE who had not responded to routine treatment in 30 minutes received NIPPV. The change in clinical symptoms, HR, RR, SBP, DBP, cardiac function and arterial blood gas （ pH, PaO2, PaCO2, SatO2） before and after NIPPV were monitored and analyzed. Results The clinical symptoms and cardiac function of 22 patients were improved significantly after the treatment of NIPPV. The HR,RR became slower （P〈0. 001）; SBP,DBP were lower（ P〈0.001）;pH,PaO2,SatO2 were higher（P〈0.001）, The efficiency rate was 91. 67%, Conclusion NIPPV could improve the syrup toms,cardiac function,and hypoxemia for the patients with ACPE. It is effective and safe.