难治性肠易激综合征患者精神心理因素分析

The psychological factors of patients with refractory irritable bowel syndrome

目的探讨难治性肠易激综合征与精神心理因素的关系。方法采用汉密顿焦虑量表、汉密顿抑郁量表对30例难治性肠易激综合征患者(研究组)与30例正常健康者(对照组)进行评定分析;汉密顿焦虑量表总分>14分为焦虑症,汉密顿抑郁量表总分>20分为抑郁症。结果汉密顿焦虑量表、汉密顿抑郁量表评分研究组均显著高于对照组(t=5.922,10.48,P均<0.01)。汉密顿焦虑量表总分>14分研究组83.3%,对照组为16.7%(χ2=27.15,P<0.01);汉密顿抑郁量表总分>20分研究组为76.7%,对照组为10.0%(χ2=26.67,P<0.01)。结论难治性肠易激综合征患者存在不同程度的焦虑抑郁状况,可根据具体情况给予心理治疗及抗焦虑、抗抑郁治疗。

Objective To explore the relationship between refractory irritable bowel syndrome（IBS） and psychological factors. Methods Evaluations and analyses were conducted with the Hamilton Anxiety Scale （HAMA） and the Hamilton Depression Scale（HAMD） in 30 patients with the refractory IBS（research group） and 30 normal healthy persons（control group）. Patients with the total HAMA score ）14 were anxiety and ones with the HAMD score ）20 depression. Results Scores of both the HAMA and the HAMD were significantly higher in the research than in the control group（P〈0.01）. The total HAMA score was ）14 in 83.3% of the research and 16.7% of the control（P〈0.01） ;the total HAMD score was ）20 in 76.7G of the research and 10. 0% of the control（P〈0. 01）. Conclusion Refractory IBS patients have different degree of anxiuos-depressive states and may give psychological, antianxiety and antidepressive treatment.