克罗恩病患者饮食习惯的研究

Research on diet in Crohn's diseases

目的旨在探查克罗恩病(CD)发生相关的膳食危险因素。方法采用1:4的病例对照研究方法,分析51例CD患者和204例对照的膳食因素,分别是:是否常吃奶类、豆类、鱼类、蛋类、禽类、水果、水果是否削皮、是否常吃蔬菜、腌渍类食物、食用油的的选择、甜食、冷饮及茶类。对CD可能的膳食危险因素进行单因素和多因素条件logistic回归分析。结果发现下列膳食因素可能为CD危险因素:牛奶(aOR=2.10);豆类(OR=2.20,aOR=2.19);鱼类(OR=3.30,aOR=3.89);蛋类(OR=3.11,aOR=3.13);水果(OR=2.25,aOR=2.64)。结论常饮牛奶、常吃蛋类可能是CD的危险因素,而少吃或不吃豆类、鱼类、水果亦可能与克罗恩病有一定的关系。

Objective To explore the potential relevant diet risk factors of Crohn＇ s disease（CD）. Methods A case-control study was used to collect the diet information from 51 CD cases and 204 controls. Diet information included milk, bean, fish, egg, poultry, fruit, fruit peeling, vegetable, preserved foods, editable oil, sweet foods, iced drinking and tea. The possible risk factors were analysed by simple and multiple factors logistic regression methods. Results Five factors had statistical significance,including milk（ aOR = 2. 10） , bean （ OR = 2.20, aOR = 2. 19） , fish（ OR = 3.30, aOR=3.89）, egg（OR=3.11, aOR=3.13）, fruit（OR=2.25, aOR =2.64）.Conclusion These results suggest that more daily consumption of milk and eggs are the risk factors of CD,while those with less daily consumption of bean,fish and fruit are among vulnerable groups of CD.