新生儿黄疸的胆红素浓度与碳氧血红蛋白及血氧饱和度关系研究

THE RELATIONSHIP BETWEEN SERUM BILIRUBIN CONCENTRATION WITH CARBOXYHEMOGLOBIN AND OXYGEN SATURATION IN JAUNDICED NEONATES

对２２例新生儿黄疸患儿同步监测血中碳氧血红蛋白、血氧饱和度及胆红素浓度。发现随胆红素浓度增加，血中碳氧血红蛋白同时增加，两者呈线性正相关（Ｐ＜０．０５）。胆红素＞３４２μｍｏｌ／Ｌ组患儿的血氧饱和度低于胆红素＜２０５．２μｍｏｌ／Ｌ（Ｐ＜０．０５）。本研究证实监测血中碳氧血红蛋白可准确反映出胆红素分解代谢。

Serum bilirubin,carboxyhemoglobin(COHB) and oxygen saturation were simultaneously determined in 22 jaundiced term babies The results demonstrated a positive linear relationship between serum TB and COHB Also,the oxygen saturation of the babies whose TB>342 μmol/L was significantly lower that those whose TB<205 2 μmol/L( P <0 05)。This study showed that the determination of serum COHB can accurately reflect the catabolism of bilirubin