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分枝杆菌多糖治疗支气管哮喘的临床研究 被引量:1

A Clinic Study of Mycobacterial Polysaccharides on Treatment of Bronchial Asthma
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摘要 对52例支气管哮喘发作期患者进行了外周血T细胞亚群、IgG4、IgE、sIL-2R、ACTH及皮质醇的测定。结果显示哮喘发作期IgG4、IgE、sIL-2R及ACTH均显著升高,提示哮喘患者存在细胞免疫及内分泌功能的异常。将分枝杆菌多糖(MPS)用于32例哮喘患者的治疗,结果与20例常规治疗组比较,MPS组CD4+/CD8+比值明显升高,IgG4和sIL-2R显著下降,而皮质醇和ACTH无明显变化。 cell subgroup,IgG 4 ,IgE,sIL 2R,ACTH and cortisol in 52 patients peripheral blood with bronchial asthma onset phase,as well as 50 controls were measured.The levels of IgG 4 ,IgE,sIL 2R and ACTH in asthma patients were significantly higher compared to those of controls.The results suggest abnormality of cell immunity and endocrinic function in asthma onset phase.52 patients were divided into 2 groups,32 were treated with MPS,20 with regular therapy.The values of CD 4 +/CD 8 + in 32 patients after treatment with MPS greatly increased and the levels of IgG 4 ,sIL 2R decreased,but ACTH,cortisol did not change.
出处 《首都医科大学学报》 CAS 1997年第1期37-40,共4页 Journal of Capital Medical University
关键词 哮喘 分枝杆菌多糖 bronchial asthma IgG 4 IgE sIL 2R T cell subgroup ACTH cortisol
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