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肾素-血管紧张素系统及其代谢片段间相互作用的研究概况

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摘要 1 血管紧张素主要代谢产物及生物学作用 血管紧张素原在肝脏合成并分泌入血,经肾小球旁细胞分泌的肾素裂解成十肽的Ang Ⅰ,在氨基肽酶(Aminopep tidase,AMP)、ACE、ACE2和中性内肽酶(Neutralendopep tidase,NEP)作用下分别生成去天门冬氨酸AngⅠ、AngⅡ和Ang1-7,随后由不同的酶进一步水解生成一系列代谢产物,包括Ang Ⅲ、Ang Ⅳ、
作者 杨德玲
机构地区 山东大学医学院
出处 《实用医药杂志》 2007年第8期992-994,共3页 Practical Journal of Medicine & Pharmacy
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