情绪负启动任务中抑郁个体的抑制机制研究

Inhibition Mechanism of Depressed Individuals in Negative Affective Priming Task

目的:在情绪负启动任务中探讨抑郁个体和正常被试对正、负情绪词抑制方面的差异。方法:抑郁组和正常组各25名被试在情绪负启动实验范式下对靶子词的效价进行评价,对两组被试在探测显示中正、负性靶子词的反应时间进行分析。结果:与控制条件相比,正常组被试在负启动条件下对探测显示中负性靶子词的反应时间更长(642.9±62.0/620.3±53.6,t=3.05,P<0.006),而抑郁个体只表现在对探测显示中正性靶子词反应时的延长(602.2±73.6/570.4±58.3,t(24)=3.88,P<0.001),对负性靶子词未出现负启动效应(t(24)=-1.92,P>0.05)。结论:抑郁个体对负性信息存在抑制功能障碍,对正性信息未存在抑制功能障碍,对负性信息的偏向与选择性注意中的维持/分离过程有关。

Objective： To study the differences of inhihition mechanism between non-depressed suhjects and depressed individuals in a negative affective priming task. Methods： 25 non-depressed suhjects and 25 depressed individuals evaluated the valence of target words in probe trial of the affective evaluation task and response time of positive and negative target words were recorded and analyzed. Results： Non-depressed suhjects response slower to positive and negative target words in probe trial under the condition of negative priming compared with control condition （ 642. 9 ± 62.0/620. 3 ± 53. 6, t = 3.05, P 〈 0. 006 ） , while depressed individuals only response slower to positive target words 1602. 2 ± 73.6/570.4 ± 58. 3, t = 3.88, P 〈 0. 001 ） and fail to show negative priming in negative target in probe trial （t = - 1.92, P 〉 0. 05 ） . Conclusion： depressed individuals are only associated with inhibitory deficit for negative information.