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膜联蛋白Ⅰ在子宫内膜异位症患者在位内膜组织中的表达变化及其意义 被引量:1

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摘要 子宫内膜异位症(内异症)是育龄妇女的常见病,发病率达10%。虽然,内异症是良性病变,但其病理过程表现出浸润、转移等恶性疾病的特征。目前,有关内异症发生的分子机制尚不清楚。我们利用蛋白质组学研究发现,膜联蛋白家族成员——膜联蛋白Ⅰ(annexinⅠ)可能为内异症疾病相关蛋白。本研究采用免疫组化、实时定量PCR及蛋白印迹的方法,检测annexinⅠ在非内异症患者子宫内膜和内异症患者在位内膜中的表达情况,旨在探讨annexinⅠ在内异症发病中的作用。
出处 《中华妇产科杂志》 CAS CSCD 北大核心 2007年第10期705-706,共2页 Chinese Journal of Obstetrics and Gynecology
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参考文献9

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