高度近视眼16层螺旋CT灌注成像研究

Clinical Study of Pro 16-slice Spiral CT Perfusion Imaging for High Myopia

目的:探讨16层螺旋CT灌注成像技术对高度近视眼眼环组织微循环血流动力学的研究。方法:对28例53只高度近视眼和32例64只正视眼,采用GE Lightspeed pro16层螺旋CT机行CT灌注扫描,获取眼球赤道后眼环血容量值(BV),建立数据库用SPSS10.0进行统计学分析。结果:高度近视眼赤道后部眼环BV值均值(4.61±1.48)ml/100g,正视眼为(7.72±1.92)ml/100g2组BV值差异具有显著性意义P<0.01。提示该区域血管的大小、多少和毛细血管开放数量存在明显差异;眼球屈光度与眼环CT灌注BV值呈正相关(r=0.793,P<0.01),即随近视屈光度数增加,眼环灌注BV值减少。结论:16层螺旋CT灌注成像眼环BV值能反映高度近视眼眼环组织微循环内血流动力学变化,是一种较好的定量检测方法。

Purpose： To study the hemodynamics of the eye-ring＇s microcirculation in patients with high myopia through 16-slice spiral CT perfusion image. Methods： Twenty-eight patients （53 eyes） with high myopia and 32 cases with emmetropia （64 eyes） in control group were examined by GE lightspeed pro 16-slice spiral CT. The perfusion image and the blood volume （BV） of the posterior equatorial eye-ring were obtained and analyzed by SPSS 10.0 software. Results： The BV of high myopia （4.61±1.48）ml/100 g is significantly less than that of the control group （7.72±1.92）ml/100 g （P〈 0.01 ）. It implies that the quantity of the small vessel and capillary in the eye-ring of the patient with high myopia is less than that of the control group. The diopter of high myopia has a significantly positive correlation with the BV of the posterior equatorial eye-ring （r =0.793, P〈0.01 ）. Conclusion： The perfusion image of 16-slice spiral CT is a quantitive method to evaluate the hemodynamics of the high myopia eye-ring＇s microcirculation.