抗精子抗体对不孕不育和流产患者的影响

Effect of Anti-sperm Antibodies on Infertile Sterile and Miscarriage Patients

目的为探讨抗精子抗体(AsAb)在不孕不育流产中的作用。方法采用快速抗精子抗体ELISA试剂盒检测不孕不育流产患者AsAb。结果在不孕不育患者中AsAb阳性率女性明显高于男性,其中,原发不孕不育患者中男性阳性率为12.59%(34/270),女性检出率29.62%(32/108);继发不育患者中男性阳性率为21.42%(3/14),女性检出率37.5%(6/16);多次流产患者中,男性检出率18.51%(5/27),女性为31.25%(5/16)。与对照组比较(P<0.05),具有显著性差异。结论AsAb检测对不孕不育的诊断具有重要意义。

Objective To investigate the effect of anti-sperm antibodies（AsAb） on infertile sterile and miscarriage patient. Methods We examine infertile sterile and miscarriage patient＇ s AsAb with the method of fast anti-sperm antibody ELISA reagent box. Results Women AsAb＇ s positive rate is obviously higher than men among infertile sterile patient. Men AsAb＇ s positive rate is 12.59% （34/270）, and women＇ s is 29.62% （32/108） among primary infertile sterile patients, and men＇ s is 21.42% （3/14）, while women＇s is 37.5% （6/16） among secondary infertile sterile patients. Among the patients who have aborted more than one time, men AsAb＇s positive rate is 19.51% （5/27）, and women＇s is 31.25% （5/16）. Compared with contrasting groups, there are significance differences （P 〈 0.05）. Conclusion It is significant to infertile sterile diagnosis to examine AsAb.