摘要
目的探讨抗心磷脂抗体(ACA)与癫痫发病的关系。方法比较48例癫痫病人及44例健康体检者血清中ACA阳性率。结果癫痫组ACA阳性率较对照组显著增高(χ2=12.64,P<0.01);服用抗痫药3个月后癫痫病人血清中ACA阳性率与服药前相比无明显差异。结论抗心磷脂抗体与癫痫发病可能相关,抗心磷脂抗体可能是癫痫的致病因素之一。
Objective To study the relationship between anticardiolipin antibodies（ACA） and epilepsy. Methods ACA was measured by using ELISA in 48 patients and 44 healthy subjects. Results The ACA level was higher in the patients than that of the healthy controls（χ^2=12.64,P〈0.01）.The difference of ACA level was not significant after taking anticonvulsants for three months compared with before medication. Conclusion ACA may be associated with epilepsy,which could probably be one of the independent risk factors of the disease.
出处
《齐鲁医学杂志》
2007年第5期423-424,共2页
Medical Journal of Qilu
关键词
抗体
抗磷脂
癫痫
免疫组织化学
antibodies,antiphospholipid
epilepsy
immunohistochemistry
