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Optineurin在POAG发病机制中作用的最新研究 被引量:1

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作者 曾艳彩 陈飞
出处 《华南国防医学杂志》 CAS 2007年第5期67-69,共3页 Military Medical Journal of South China
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  • 1[1]Rezaie T,Child A,Hitchings R,et al.Adult-onset primary openangle glaucoma caused by mutations in optineurin[J].Science,2002,295(5557):1077-1079
  • 2[2]Vittitow J,Borras T.Expression of optineurin a glaucoma-linked gene,is influenced by elevated intraocular pressure[J].Biochem Biophys Res Commun,2002,298(1):67-74
  • 3[3]Kamphuis W,Schneemann A.Optineurin gene expression level in human trabecular meshwork does not change in response to pressure elevation[J].Ophthalmic Res,2003,35(2):93-96
  • 4[4]Obazawa M,Mashima Y,Sanuki N,et al.Analysis of porcine optineurin and myocilin expression in trabecular meshwork cells and astrocytes from optic nerve head[J].Invest Ophthalmol and Vis Sci,2004,45(8):2652-2659
  • 5[5]Li Y,Kang J,Horwitz MS.Interaction of an adenovirus E3 14.7-Kilodalton protein with a novel tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains[J].Mol Cell Biol,1998,18(3):1601-1610
  • 6[6]Kroeber M,Ohlmann A,Russell P,et al.Transgenic studies on the role of optineurin in the mouse eye[J].Exp Eye Res,2006,82(6):1075-1085
  • 7[7]De Marco N,Buono M,Troise F,et al.Optineurin increases cell survival and translocates to the nucleus in a Rab8-dependent manner upon an apoptotic stimulus[J].J Biol Chem,2006,281(23):16147-16156
  • 8[8]Park BC,Shen X,Samaraweera M,et al.Studies of optineurin a glaucoma gene:Golgi fragmentation and cell death from overexpression of wild-type and mutant optineurin in two ocular cell types[J].Am J Pathol,2006,169(6):1976-1989
  • 9[9]Schwamborn K,Weil R,Courtois J,et al.Phorbol esters and cytokines regulate the expression of the NEMO-related protein,a molecule involved in a NF-kB independent pathway[J].J Biol Chem,2000,275(30):22780-22789
  • 10[10]Hattula K,Peranen J.FIP-2 a coiled-coil protein links huntingtin to Rab8 and modulates cellular morphogenesis[J].Curr Biol,2000,10(24):1603-1606

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