摘要
目的研究柴胡静脉乳剂的解热、镇痛作用。方法分别采用2,4-二硝基苯酚致热大鼠模型、醋酸致小鼠扭体反应及小鼠热板致痛模型,研究柴胡静脉乳剂的解热、镇痛作用。结果柴胡静脉乳剂可以降低由2,4-二硝基苯酚引起的大鼠体温升高,减少醋酸致小鼠扭体反应次数及提高小鼠热板试验痛阈值。结论柴胡静脉乳剂具有解热、镇痛作用。
Objective To investigate the relieve fever and analgesic effect of Bupleurum Chinese emulsion （BE）. Methods Animal models of fever were made by 2, 4-dinitrophenol, the writhing response of mice were induced by acetic acid, and the model of pained reaction induced by hot place were made, and the body temperature of rats, writhing frequency and reaction time of hot place were measured. Results The body temperature of rats that had been hoisted by 2, 4-dinitrophenol was depressed, and the writhing frequency caused by acetic acid reduced, the threshold value of hot place examination of mice were advanced. Conclusion BE has the relieve fever and analgesic effect.
出处
《实用药物与临床》
CAS
2007年第5期270-272,共3页
Practical Pharmacy and Clinical Remedies
关键词
柴胡静脉乳剂
解热
镇痛
Bupleurum Chinense emulsion （BE）
Relieve fever
Analgesic effect
