1Bone RC, Balk RA, Cerra FB et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians Isociety of Critical Care Medicine. Chest, 1992, 101 (6) : 1644.
2Bone RC. Sepsis, sepsis syndrome and the systemic inflammatory syndrome (SIRS). JAMA, 1995,273(2): 155.
3Way LW ed. Current Surgical Diagnosis and Treatment. 10ed. Norwalk:App leton, 1994,94-128.
7Schwartz MD, Moore EE, Moore FAet al. Nuclear factor - kappa B is activated in alveolar macrophages from patients with acute respiratory distress syndrome. Crit Care IVied, 1996,24(8) : 1285.
8Tritos N,Kitraki E, Philippidis H et al. Neurotransmitter modulation of glucocorticoid receptor mRNA levels in the rat hippocampus. J Neuroendocrindogy, 1999,69(5) : 324.
10Blackwell TS, Blackwell TR, HokdenN EP et al. In vivo antioxidant treatment suppresses NF-κB activation and neutrophilic lung inflammation. J Immunol, 1996,157 (4) : 1630.
3Terregino CA, Lopez BL, Karras DJ,et al. Endogenous mediators in emergency department patients with presumed sepsis: are level associated with progression to severe sepsis and death? [J]. Ann Emerg Med, 2000, 35(1): 26-34.
4Shames BD, Meldrum DR, Selzman CH, et al. Increased levels of myocardial IκB-α protein promote tolerance to endotoxin[J]. Am J Physiol., 1998, 275(44) : H1084 - H1091.
5Blackwell TS,Blackwell TR, Christman JW. Induction of endotoxin tolerance depletes nuclear factor- κB and suppresses its activation in rat alveolar macrophage [ J]. J Leukoc Biol,1997, 62(6) : 885 - 891.
6Brun BC. The epidemiology of the systendc inflammatory response[J]. Intensive Care Med, 2000,26(Suppl): IS64-IS74.
7Barnes PJ, Karin M. Nuclear factor- κB - α pivotal transcription factor in chronic inflammatory diseases[ J ]. New Engl J Med, 1997, 336(5): 1066-1071.
8Pavassilion AG. Transcriotion factors. N Engl I Med, 1995, 332,45.
9Katsuhiro Zen, Aly Karsan, Thomas Eunson et al. Lipopolysaccharideinduced NF-κB activation in human endothelial cells involves degradation of IκB-abut not IκB-β. Exp Cell Res, 1998, 243:425.
10Chen F, Lu YJ, Douglas CK et al. Calpain contributes to silica-induced IκB-adegradation and nuclear factor-κB activation. Arch Biochem Biophys,1997, 342:383.
