血脂比值与冠脉狭窄程度的相关分析

Correlation Studying on Lipid and Blood Lipids Ratio and the Degree of Coronary Artery Stenosis of CAD

目的探讨冠心病患者的血脂比值和单项血脂与冠脉狭窄严重程度的相关性。方法对已行冠状动脉造影的阳性病人(最少有一支血管狭窄≥50%)的各项血脂及其比值进行检测,并与其冠脉狭窄程度进行相关分析。结果①在单项血脂中,TG、CHO、LDL、LP(a)均与冠脉狭窄程度呈正相关,而HDL和apoA与冠脉狭窄程度呈负相关。②在血脂比值中,CHO/HDL、apoB/apoA TG/apoA、CHO/apoA LDL/apoA值均随冠脉狭窄程度加重而增加,且差异有显著性意义。③血脂比值比单项血脂反映CAD的敏感度更高。结论:对于CAD患者,血脂比值反映冠脉狭窄的严重程度较单项血脂更敏感更早期。

Object： To study the relationship of individual lipid and Blood lipids ratio and the degree of coronary artery stenosis of coronary atherosclerosis heart disease （CAD）. Method： 227 patients with positive resuits in coronary angiogram （at least one artery is more narrow than 50%） were recuited, and investigated correlation of the individual and blood lipid ratio and results by coronary angiography. Conclusion： ① The studying showed a positive correlation between the degree of coronary artery stenosis and TG, CHO, LDL, LP（a） and a negative correlation between the degree of coronary artery stenosis and HDL and apo A. ② In the study of blood lipid ratio ,there were positive correlation between CHO/HDL and TG/HDL and the degree of coronary artery stenosis. ③ The ratio of CHO/HDL,apoB/apoA TG/apoA,CHO/apoA LDL/apoA can understand the degree of coronary artery stenosis more easy than individual blood lipids. ④ Blood lipids ratio have better correlation with the degree of coronary artery stenosis early than individual blood lipids Result ： For CAD patients, blood lipid ratio reflect Degree of Coronary Artery Stenosis of CAD more sensitive and early than individual blood lipid.