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低浓度布吡卡因和利多卡因混合液用于臂丛神经阻滞麻醉 被引量:1

Use of Low Concentration Bupivacaine-Lidocaine Mixture in the Plexus Brachialis Block Anesthesia
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摘要 本文将40例手及前臂手术的成年病人随机分为两组,采取锁骨上经路的臂丛神经阻滞麻醉,分别使用0.15%布吡卡因+1%利多卡因含1/200000肾上腺素、0.25%布吡卡因+1%利多卡因含1/200000肾上腺素的混合液,注射容积小于或等于0.5ml/kg,结果麻醉效果差别无显著意义(P>0.05),这样既减少了局麻药的用量,又提高了麻醉的安全性。 The article reports 40 patients (17-45y) who performed surgical operations of forearm or hand using a plexus brachialis block anesthesia by an approach of supraclaricularis. The patients were divided randomly into 2 groups, every group being 20 patients. Group 1 (trial) had an injection of the mixture contained 0.15% bupivacaine, 1% lidocaine and 1/200 thousand epinephrine. Group Ⅱ (control) had an injection of the mixture contained 0.25% bupivacaine, 1% lidocaine and 1/200 thousand epinephrine. All patients employed a dose of 0.5ml/kg of local anesthetic injection with a maximum of less than 30ml. The result showed that analgesic effects in both groups made no difference (P>0.05), only the anesthesia duration in group I (366.1min) was markedly shorter than that in group Ⅱ(432.25min). The authors consider that low concentration bupivacaine-lidocaine mixture for plexus brachialis block is a safe and effective method for forearm or hand operation with the except of replantation of severed limb or finger owing to need of a longer operation time.
出处 《贵阳医学院学报》 CAS 1990年第1期64-66,共3页 Journal of Guiyang Medical College
关键词 布吡卡因 利多卡因 传导麻醉 臂丛 bupivacaine lidocaine anesthesia, conduction brachial plexus
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  • 1Kolesnikov YA,Jain S,Wilson R,et al.Peripheral morphine analgesia:synergy with central sites and a target of morphine tolerance[J].J pharmacol Exp Ther,1996,279:502-506.
  • 2Antonijevie I,Mousa SA,Stein C,et al.Perineurial defect and peripheral opioid analgesia in inflammation[J].J Neurosci,1995,15:165-172.
  • 3Stein C,Comisel K,Haimerl E.Analgesic effect of intraarticular morphine after arthroscopic knee surgery[J].N Eng1 J Med,1991,325:1123-1126.
  • 4Likar R,Schafer M,Paulak F,et al.Intraaricular morphine analgesia in chronic pain patients with osteoarthritis[J].Anesth Analg,1997,84:1313-1317.

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