蚕蛹多糖对小鼠免疫功能的影响

Effect of polysaccharide of silkworm pupa on immunological function in mice

目的:通过测定蚕蛹多糖对小鼠淋巴细胞增殖、巨噬细胞吞噬活力及溶血素生成的影响,研究蚕蛹多糖对小鼠免疫功能的影响。方法:采用免疫重量法计算脾脏和胸腺指数、巨噬细胞测定法及溶血素测定法、淋巴细胞转化实验、MTT法测定。结果:蚕蛹多糖能明显增强B淋巴细胞和T淋巴细胞的增殖,促进小鼠巨噬细胞的吞噬活力和溶血素生成。结论:蚕蛹多糖能增强小鼠的细胞免疫和体液免疫功能。

Objective ： To investigate the effect of polysacchaide of silkworm pupa （PSP） on immunological function in mice. Methods： To weight immune organs, detect macrophage phagocytosis and hemolysin antibody production, lymphocyte transfermation and MTT. Results： PSP raised significantly the proliferation of T and B lymphocytes, macrophage phagocytosis and hemolysin antibody production in mice. Conclusion： PSP increased cellular and humoral immunity in mice.