摘要
目的:通过测定蚕蛹多糖对小鼠淋巴细胞增殖、巨噬细胞吞噬活力及溶血素生成的影响,研究蚕蛹多糖对小鼠免疫功能的影响。方法:采用免疫重量法计算脾脏和胸腺指数、巨噬细胞测定法及溶血素测定法、淋巴细胞转化实验、MTT法测定。结果:蚕蛹多糖能明显增强B淋巴细胞和T淋巴细胞的增殖,促进小鼠巨噬细胞的吞噬活力和溶血素生成。结论:蚕蛹多糖能增强小鼠的细胞免疫和体液免疫功能。
Objective : To investigate the effect of polysacchaide of silkworm pupa (PSP) on immunological function in mice. Methods: To weight immune organs, detect macrophage phagocytosis and hemolysin antibody production, lymphocyte transfermation and MTT. Results: PSP raised significantly the proliferation of T and B lymphocytes, macrophage phagocytosis and hemolysin antibody production in mice. Conclusion: PSP increased cellular and humoral immunity in mice.
出处
《江苏大学学报(医学版)》
CAS
2007年第5期373-375,共3页
Journal of Jiangsu University:Medicine Edition
基金
江苏省教育厅自然科学基金资助项目(2004SW002J)
镇江市产学研资助项目(2006SW068J)
关键词
蚕蛹多糖
免疫功能
小鼠
polysaccharide of silkworm pupa
immunological function
mice