小儿紫癜性肾炎94例临床分析

Clinical Analysis and Follow up Survey of 94 Children with Anaphylactoid Purpura Nephritis

本文对184例过敏性紫癜中合并肾炎的94例(51.1％)进行了分析,其主要临床表现为:皮肤紫癜(100％)、腹痛和(或)便血(66.0%),关节炎(60.0％)、尿改变(100％)、浮肿(23.4％)、高血压(16.0％)和肉眼血尿(7.4％)。近期治愈和好转率共87.2％。随访出院后1～13年的30例,临床痊愈24例、未愈4例、死亡2例。文中强调长期随访。临床表现兼有显著浮肿,肾号功不良及肉眼血尿者预后不良。

Ninty-four cases with anaphylactoid purpura nephritis (APN) out of 184 cases with anaphylactoid purpura (AP) who admitted in our department from January 1975 through December 1987 are reported. The main signs were: skin purpura(100%), abdominal pain and/or gross blood stool(66%), arthritis (60%), change of urine (100%), edema(23.4%), hypertension (16%), macroscopic hematuria (7.4%). Thirty cases with APN were follow up for 1-13 years and the results were: clinical recovery 24, persistent nephritis 2,nephrotic syndrome 2 and died from progressive renal failure 2. That the patients had heavy edema, renal insufficiency and macroscopic hematuria lndicated a poor prognosis.