运动神经元病及运动神经元病综合征31例临床分析
被引量:1
摘要
运动神经元病(MND)为选择性侵犯运动神经元的神经系统变性病,主要表现为骨骼肌萎缩、无力,直至呼吸肌麻痹而死亡。临床表现为运动神经元病(MND)而有明确病因者,称为运动神经元病综合征(MNDS)。本文分析了1990年至2006年,我院31例运动神经元病(MND)及运动神经元病综合征(MNDS)患者的临床资料,并探讨其病因及发病机制。现报告如下。
出处
《基层医学论坛(B版)》
2007年第11期964-965,共2页
Public Medical Forum Magazine
二级参考文献13
-
1Brooks BR. EI escorial world federation of neurology criteria for the diagnosis of amyotrophic lateral sclerosis. J Neurol Sci, 1994, 124(suppl): 96.
-
2Riviere M, Meininger V, Zeisser P, et al. An analysis of extended sunival in patients with amyotrophic lateral sclerosis created with riluzole.Arch Neural, 1998, 55(4): 526.
-
3Favaron M, Manev H, Alho H, et al. Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex. Proc Natl Acad Sci U S A, 1998, 85(19): 7351.
-
4Debelleroche J, Recorgati A, Rose CF. Elevated levels of amino acids in the motor neuron disease patients. Neurochem Pathol, 1984, 2(1):1.
-
5Rothstein JD, Kuncl R, Chaundhry V, et al. Excictatory amino acids in amyotrophic lateral sclerosis: an uplate. Ann Neural, 1991, 30(1): 224.
-
6Shaw PJ, Forrest V, Ince PC,, et al. CSF and plasma amino acid level in motor neuron disease: elevation of CSF glutamate in a subest of patients.Neurodegeneration, 1995, 4(2): 209.
-
7Niebroj DI, Janik P. Amino acids acting as transmitters in amyotrophic sclerosis. Acta Neurol Scand, 1999, 100( 1 ) : 6.
-
8Patten BM, Harati Y, Acosta L, et al. Free amino acid levels in amyotrophic lateral sclerosis. Ann Neurol, 1978, 3(2): 305.
-
9Perr TL, Krieger C, Hansen S, et al. Amyotrophic lateral sclerosis:amino acid levels in plasma and cerebrospinal fluid. Ann Neurol, 1990,28(1) : 12.
-
10Camu W, Billiard M. Blady-Mouliner M. Fasting plasma and CSF amino acid level in amyotrophic lateral sclerosis: a subtype analysis. Acta Noarol Scand, 1993, 88(1): 51.
共引文献5
-
1樊汉青,蒋雨平,朱秋毓.肌萎缩侧索硬化患者血浆和脑脊液谷氨酸改变及利鲁唑对血浆谷氨酸的影响[J].中国临床神经科学,2004,12(3):236-238. 被引量:1
-
2许蕾,刘亚玲,郭艳苏,李春岩.运动神经元病及运动神经元病综合征37例临床分析[J].中国神经精神疾病杂志,2005,31(5):346-346. 被引量:1
-
3肖向建,刘卫刚,李敏,马征,李春岩.谷氨酸转运抑制剂对大鼠培养脑片皮层锥体细胞的影响[J].基础医学与临床,2006,26(1):51-54. 被引量:2
-
4刘春华,王维治.头孢曲松钠对谷氨酸神经毒性的影响及其机制[J].中国神经精神疾病杂志,2007,33(1):42-45. 被引量:2
-
5杨娟,张成,任惠.肌萎缩侧索硬化症患者脑脊液和血液中的生物学标记研究进展[J].国际神经病学神经外科学杂志,2009,36(5):433-436. 被引量:5
同被引文献10
-
1曹霞,常高峰,尚明谦.以呼吸肌麻痹为主要表现的成人型脊髓性肌萎缩症1例[J].疑难病杂志,2008,7(7):437-438. 被引量:2
-
2Steier J,Kaul S,Seymour J,et al.The value of multiple tests ofrespiratory muscle strength. Thorax . 2007
-
3de Carvalho M,Matias T,Coelho F,et al.Motor neuron disease presenting with respiratory failure. Journal of the Neurological Sciences . 1996
-
4Chen R,Grand’Maison F,Brown JD,et al.Motor neuron disease presenting as acute respiratory failure: electrophysiological studies. Muscle and Nerve . 1997
-
5Sasaki S.Phenotypes in ALS-clinical features and pathology. Brain and Nerve . 2007
-
6Pinto S,de Carvalho M.Machado-Joseph disease presenting asmotor neuron disease. . 2007
-
7American Thoracic Society/European Respiratory Society.ATS/ERS Statement on respiratory muscle testing. American Journal of Respiratory and Critical Care Medicine . 2002
-
8Luo YM,HartN,Mustfa N,et al.Reproducibility of twitch and sniff transdiaphragmatic pressures. Respiratory Physiology and Neurobiology . 2002
-
9Luo YM,Moxham J.Measurement of neural respiratory drive in patients with COPD. Respiratory Physiology and Neurobiology . 2005
-
10吴碧华,龙存国,杨得本,李秋茹,张小东,许可.运动神经元疾病29例临床分析及文献复习[J].四川医学,2002,23(9):947-948. 被引量:3
-
1许蕾,刘亚玲,郭艳苏,李春岩.运动神经元病及运动神经元病综合征37例临床分析[J].中国神经精神疾病杂志,2005,31(5):346-346. 被引量:1
-
2王者晋,商军科,苗建亭,王爽.运动神经元病及运动神经元病综合征[J].中国临床康复,2002,6(13):1908-1909. 被引量:5