摘要
目的:观察氟罗沙星对照氧氟沙星治疗肺部感染的疗效。方法:38例痰菌培养阳性的肺部感染病人分2组,治疗组22例(男性13例,女性9例,年龄64±s9a)用氟罗沙星0.4g,po,qd×6d。对照组16例(男性11例,女性5例,年龄66±7a)用氧氟沙星0.2g,po,bid×6d。结果:前者有效率77%,菌株清除率77%。后者分别为75%和81%。2组无显著性差异(P>0.05)。结论:氟罗沙星是治疗肺部感染的有效药物,无显著不良反应。
AIM: To observe the therapeutic effect of fleroxacin in treating pulmonary infections. METHODS: Thirty-eight patients with pulmonary infections and positive sputum cultures were divided into 2 groups. Twenty-two patients (M 13, F 9, age 64±s 9 a) in treatment group received fleroxacin 0.4 g, po, qd for 6 d. Sixteen patients (M 11, F 5, age 66±7 a) received ofloxacin 0.2 g, po, bid for 6 d as control. RESULTS: The effective rate and the bacteria clear rate of the treatment group were 77% and 77%, respectively, and of the control group were 75% and 81%, respectively. No significant difference was found between the 2 groups (P>0.05). CONCLUSION: Fleroxacin is an effective drug for treatment of pulmonary infections without obvious adverse reactions.
出处
《新药与临床》
CSCD
北大核心
1997年第2期85-86,共2页