肾移植超急性排斥反应13例次分析

Hyperacute rejection in renal transplantation: report of 13 cases

报告1978年8月～1994年12月间共做尸体肾移植570例次,其中发生超急性排斥反应(HAR)11例13次(13例次),均经病理证实,发生率为2.3%.移植肾于术中或术后短期予以摘除.并结合临床资料对HAR的发生机理、危险因素、鉴别诊断及预防等进行分析,认为HAR的发生与受者体内的预存抗体有关,反复输血、多次妊娠、再次肾移植是HAR的诱发因素,术前系统、准确的配型有助于减少HAR的发生.

570 cases of cadaveric renal transplantation were performed from August 1978 to December 1994 in our hospital. Hyperacute rejection(HAR) occurred in 13 grafts of 11 patients (2. 3%), all of whom were comfirmed by pathology and treafed by nephrectomy. The mechnism, risk factors and prevention of HAR are discussed.