静注免疫球蛋白对输血后丙型肝炎病毒感染的预防作用

Intravenous injection of immunoglobulin prevent hepatitis C virus infection after posttransfusion

目的了解静注免疫球蛋白（IVIG）对输血后丙型肝炎病毒（HCV）感染的预防作用。方法68例血液病患儿分为2组，IVIG组38例，均输往有IVIG和其他血液成分;对照组30例，单纯输血者。HCV-Ab采用酶联免疫法，HCV-RNA采用PCR法。结果IVIG组部分病例出现被动输入的HCV-Ah，HCV-RNA阴性，无HCV感染病例;对照组2例发生HCV感染，HCV-Ab和HCV-RNA阳性。结论本研究结果提示IVIG可能有预防输血后HCV感染的作用。

Objecfive,To stucty the effect of IVIG for prevonting Posttransfusion hepatitis C virus infection.Methods: All patients(68 cases) rcccivcd blood transrusion, only 38 patients reccived as well as IVIG posttansfusion assoctated HCV infection was suiveid by HCV-Ab and HCV-RNA.Results: There was no HCV infection in the patients who accepted b1ood transfution and TVTG: But in the patients who acccpted blood transfution only two HCV infection were detected within 1 year follow up Posttransfusion.Conclusion: The results suggested that IVIG had a ccrtion action prevent Posttransfusion hepatitis C virus infection.