还真冲剂结合西药治疗气虚血瘀型急性缺血性脑卒中临床观察

Clinical Observation of "Huanzhen Granule" Combined with Western Medicine in Treating Acute Ischemic Stroke of Qi Deficiency and Blood Stagnation

目的观察还真冲剂治疗急性缺血性脑卒中的临床疗效。方法将60例急性缺血性脑卒中气虚血瘀证型患者按入院时间随机分为治疗组和对照组,各30例。两组均采用基础治疗,治疗组加服还真冲剂,疗程均为4周,分别在治疗2周和4周时观察患者神经功能缺损程度(NIHSS)、日常生活能力状况(Barthel指数)、日常生活依赖程度(MRS)变化情况。结果治疗2周后两组之间NIHSS、Barthel指数和MRS比较无显著性差异(P>0.05);治疗4周后治疗组NIHSS明显低于对照组(P<0.05),Barthel指数总分明显高于对照组(P<0.05),两组之间MRS比较无显著性差异(P>0.05)。结论还真冲剂可改善气虚血瘀证型缺血性脑卒中患者神经功能缺损状况和日常生活能力。

Objective To observe the effect of ＂Huanzhen Granule＂ in treating acute ischemic stroke by clinical research. Methods Sixty subjects were randomly allocated into the treatment group in which 30 cases were treated with elementary treatment and ＂Huanzhen Granule＂ and control group in which 30 cases were treated with simple elementary treatment, with a course of 4 weeks. NIHSS, Barthel index and MRS were observed after treatment. Results NIHSS, Barthel index and MRS were not significantly different after treatment between two groups 2 weeks later（P〉0.05）; the treatment group had lower scores of NIHSS and higher Barthel index scores when compared with the control group after 4-week treatment （P〈0.05）, but MRS was not significantly different between two groups after 4 weeks （P〉 0.05）. Conclusion ＂Huanzhen Granule＂ is effective in improving the severity of cerebral infarction and ability of dependence of patients with acute ischemic stroke of qi deficiency and blood stagnation.