摘要
目的评价除湿止痒合剂治疗湿疹的疗效,并探讨其对患者血清IL-4水平的影响。方法将90例急性、亚急性湿疹患者随机分为除湿止痒合剂治疗组(A组)、西可韦对照组(B组)及中西药物联合对照组(C组),每组30例;均以2周为1个疗程,2个疗程后观察各组疗效及血清IL-4水平的变化。结果①A组总有效率为83.33%,B组总有效率为63.33%,C组总有效率为86.67%,A组及C组疗效均明显优于B组(P<0.05);A组与C组间无显著性差异(P>0.05)。②A组治疗后血清IL-4水平明显下降,与治疗前比较有显著性差异(P<0.01),B组治疗前后无显著性差异(P>0.05);A组与B组比较有显著性差异(P<0.01)。结论除湿止痒合剂治疗湿疹疗效显著,对患者的免疫功能具有一定的调节作用。
Objective To observe the clinical efficacy of "Chushi Zhiyang Mixture" in the treatment of eczema and its effects on IL-4. Methods Ninety subjects were randomized into three groups, 30 cases in each group: Group A in which "Chushi Zhiyang Mixture" was given, group B in which Cetirizine was given and group C in which "Chushi Zhiyang Mixture" and Cetirizine were given, with a week in a course. The clinieal efficacy and serum IL-4 were observed. Results The total effective rate was 83.33% in group A, 63.33% in group B and 86.67% in group C: Ridit analysis showed thai the eflkeciive rates were higher in groups A and C than group B (P〈 0.05), with no difference between group A and group C. After treatment, the serum IL-4 declined in group A (P〈0.01), little in group B (P〉 0.05); there was a signifieant diffence between groups A and B (P 〈 0.01). Conclusion "Chushi Zhiyang Mixture" has positive effects on eczema and
出处
《上海中医药杂志》
北大核心
2007年第10期53-54,共2页
Shanghai Journal of Traditional Chinese Medicine