摘要
高氧肺损伤以早期肺泡炎和后期肺纤维化为特征。转化生长因子-β是一种多功能的细胞因子，控制着细胞功能的多个方面，包括细胞的增殖、分化，组织修复和细胞外基质蓄积的调控，免疫和炎症反应的调节。
Hyperoxia-induced lung injury is characterized with early alveolitis,followed by pulmonary fibrosis. Transforming growth factor-beta is a multifunctional cytokine that controls many aspects of cellular function, including cellular proliferation, differentiation, regulation of tissue repair and extracellular matrix accumulation,modulation of the immune and inflammatory responses.
出处
《国际呼吸杂志》
2007年第21期1619-1622,共4页
International Journal of Respiration
关键词
高氧
肺损伤
受体
信号转导
转化生长因子-Β
Hyperoxia
Lung injury
Receptor
Signal transduction
Transforming growth factor-beta
