多发性大动脉炎主动脉破裂尸检及文献复习

Aortic rupture in polyarteritis: an autopsy report and review of literature

目的探讨多发性大动脉炎的临床、病理学特点及鉴别诊断。方法对1例多发性大动脉炎的尸体解剖病例进行病理学检查并复习文献。结果多发性大动脉炎是主要累及主动脉及其主要分支的全血管性非特异性炎症,以动脉管壁增厚、狭窄为主要特征,急性期无特征性症状,可致节段性内膜剥离,形成致命性夹层动脉瘤。结论多发性大动脉炎急性期无特征性症状,容易误诊,对无明显原因胸痛青年患者应提高警惕。

Purpose To discuss the clinical, pathological characteristics and differential diagnosis of polyarteritis. Methods Pathological inspection was conducted in an autopsy case of a polyarteritis with review of the literature. Results Polyarteritis was whole blood vessel and non-specific inflammation that mainly involved aorta and its chief branch, Its key feature was thickening and narrow of arterial vessel wall, no characteristic symptom in acute stage but may cause endothelial segmental stripping and formed fatally dissecting aneurysm. Conclusions Polyarteritis is easily misdiagnosed because of no characteristic symptom in acute stage, The young patient who has chest pain but without obvious cause should be highly suspected.