期刊文献+

前列腺素E1治疗糖尿病肾病的研究 被引量:1

下载PDF
导出
摘要 目的观察前列腺素E1(保达新)治疗糖尿病肾病的疗效。方法将60例糖尿病肾病患者随机分为治疗组和对照组,对照组给予糖尿病常规治疗,治疗组在糖尿病常规治疗基础上加用前列腺素E1,观察两组尿蛋白、肾功能等指标的变化。结果和对照组比较,治疗组患者尿蛋白明显下降,两组治疗前后血肌酐、尿素氮无明显变化。结论前列腺素E1可以降低糖尿病肾病尿蛋白的排泄,在治疗糖尿病肾病的应用上具有广阔前景。
出处 《医药论坛杂志》 2007年第20期44-45,共2页 Journal of Medical Forum
  • 相关文献

参考文献6

二级参考文献18

  • 1张同玉,王中笑.中西医结合延缓糖尿病肾功能衰竭[J].医药论坛杂志,2005,26(21):90-90. 被引量:1
  • 2东菱精纯克栓酶(DF-521)治疗急性脑梗塞的临床研究[J].中风与神经疾病杂志,1996,13(4):213-215. 被引量:110
  • 3孔晚红,马秀萍,高慧,朱本章,施秉银.糖尿病肾病易患因素分析[J].中国糖尿病杂志,1997,5(1):55-56. 被引量:15
  • 4小林令明. 糖尿病性肾病に及ぼす低分子へぺりリンの效果. 临床的ならび实验的检讨. 糖尿病, 1998,41:1003-1007.
  • 5Ishii H, Majerus PW. Thrombomodulin is present in human plasma and urine. J Clin Invest, 1985,76:2178-2181.
  • 6由井克昌, 田中明, 诸星政治, 等. 糖尿病患者血中トロンボモヅェリンの检讨. 血清クレアチン值による补正の试. 糖尿病, 1994,37:726-730.
  • 7和田英夫 板根祥裕.血栓症:诊断と治疗の进步.Ⅱ血栓症の诊断へのアプロ—チ.血栓症早期诊断のための临床检查[J].日内会志,1997,86(6):911-914.
  • 8Cawello W,Leonhardt A,Schweer H,etal.Dose proportional pharmacokinetics of alpro-stadil (prostaglandin E1)in healthyvolunteers following intravenous infusion 〔J〕.Br J Clin Pharmacol,1995,40:273~276.
  • 9Anggard E.The biological activities of three metabolites of prostaglandin E1 〔J〕.ActaPhysiol Scand,1996,66:509~510.
  • 10Yasuda H,Maeda K,Sonobe M,et al.Metabolic effect of PGE1 analogue O1206.αCD onnerve Na+-K+-ATPase activity of rats with streptozotocin-induced diabetes is mediatedvia cAMP: possible role of cAMP in diabetic neuropathy 〔J〕.Prostaglandins,1994,47:367~378.

共引文献132

同被引文献8

  • 1傅汉菁,袁申元.胰激肽原酶在糖尿病治疗中的临床应用[J].中国实用内科杂志,2004,24(11):698-700. 被引量:40
  • 2Yang W, Lu J, Weng J, et al. Prevalence of diabetes among men and women in China [ J ]. N Engl J Med, 2010, 362(12) :1090-1101.
  • 3Wang H, Deng JL, Yue J, Li J, Hou YB. Prostaglan- din E1 for preventing the progression of diabetic kidney disease [ J ]. Cochrane Database Syst Rev, 2010, 5 :CD006872.
  • 4Maric C. Vasoactive hormones and the diabetic kidney [ J ]. Scientific World Journal,2008, 8:470-485.
  • 5Mogensen CE. The natural history of diabetic nephropathy in insulinodependent diabetics and the concept of non- glycemic treatment [ J ]. Journ Annu Diabetol Hotel Dieu, 1989:225-246.
  • 6Haffner S M, Lehto S, Ronnemsa T, et al. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infection [ J ]. N Engl J Med, 1998, 339 (4) : 229-234.
  • 7Bodin S, Chollet C, Goncalves -Mendes N,et al. Kal- likrein protects against microalbuminuria in experimental type I diabetes [ J ]. Kidney Int, 2009, 74 ( 4 ) : 395- 403.
  • 8Itoh Y, Yasui T, Kakizawa H, et al. The therapeutic effect of lipo PGE1 on diabetic neuropathy - changes in endothelin and various angiopathic factors [ J ]. Prosta- glandins Other Lipid Mediat, 2001, 66 (3) : 221-234.

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部