摘要
Wnt信号通路对控制胚胎发育起着重要作用,其异常激活参与了人类多种肿瘤的发病过程,与消化道肿瘤有着密切关系.而Wnt信号通路的拮抗剂能阻滞信号转导,抑制Wnt2信号通路的异常激活,可望为将来抗肿瘤治疗提供一条新的途径.
The Wnt signal transduction pathway plays an important role in controlling embryo development; its abnormal elevation is involved in many types of human tumorigenesis, and it has a close relationship with digestive tract tumors. Wnt antagonists can block Wnt signal transduction and inhibit its abnormal elevation, and therefore may provide a potential new anticancer therapy.
出处
《世界华人消化杂志》
CAS
北大核心
2007年第27期2880-2884,共5页
World Chinese Journal of Digestology
关键词
Wnt信号转导
消化道肿瘤
Wnt signal transduction
Digestive tract tumor
