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CT引导毁损苍白球内侧部治疗帕金森病17例分析

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摘要 目的探讨在CT导向下脑立体定向计算机辅助规划射频毁损苍白球内侧部(GPi)对帕金森病(PD)的治疗效果。方法使用南京麦迪柯科技公司98-Ⅲ型脑立体定向计算机辅助规划手术系统,对17例PD患者的头颅CTGPi的直接定位,用N-30型射频仪(西安黄河),制造一个约8毫米直径的毁损灶。结果按帕金森评定量表(Unified Parkinson Disease Rating Scale,UPDRS)运动评分,术后1周,在关状态下,术后症状改善率47.1%,在开状态下改善率41.1%,开-关症状和异动症均消失。经随访3年,显效64.7%,改善23.5%,无效11.8%。并发症:术后8小时内出现对侧肢体部分发作肌痉挛者2例(11.8%),均在3天后消失。对侧肢体轻偏瘫者1例(5.9%),2周内恢复正常,无其他并发症及死亡。结论PD患者行GPi毁损术后僵直、震颤多可消失,运动不能等症状有所改善。
出处 《立体定向和功能性神经外科杂志》 2007年第5期302-303,共2页 Chinese Journal of Stereotactic and Functional Neurosurgery
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