微机械加工微型葡萄糖传感器

MICROMACHINED GLUCOSE MICROSENSOR

用微机械加工技术和微电子平面工艺制备了微型Ｃｌａｒｋ型氧电极。外型尺寸为１５×２×０７ｍｍ３，敏感面积为１×０５ｍｍ２。在敏感区固定葡萄糖氧化酶（ＧＯＤ），构成了微型葡萄糖传感器。传感器的主要性能：灵敏度２２ｎＡ／（ｍｍｏｌ／Ｌ）；响应时间＜１ｍｉｎ，线性范围０１～１０ｍｍｏｌ／Ｌ，变动系数９７％，稳定响应在二十天以上。

A miniaturized Clark oxygen sensor with 15×2×0 7 mm 3 in size and 0 5×1 0mm 2 in sensing area was fabricated by micro machining technique and standard planar processing A glucose microsensor was developed by means of fixing GOD on the sensing area of the oxygen electrode It's sensitivity is 2 2nA/(mmol/L), response time <1 min, linear range 0 1～ 10 mmol/L, variation coefficient 9 7%, and life time > 20 days