期刊文献+

乳腺癌蛋白质组研究进展 被引量:4

Progress in proteome research of breast cancer
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摘要 乳腺癌是发生在乳房腺上皮组织的恶性肿瘤,其发病率占女性恶性肿瘤首位。近年来,蛋白质组研究广泛深入乳腺癌发病机理、临床早期诊断和治疗等各个方面。本文比较系统地综述了乳腺蛋白质组研究的样品处理、研究技术和研究成果。  Breast cancer is a malignant cancer that is developed in breast epithelial tissue. The mortality of breast cancer is at the first place in female malignant cancers. In recent years, proteome research is widely used in pathogenesis, clinical early diagnosis and treatment of breast cancer. In this review, we systematically summarized the progress of proteome research in sample treatment, experiment technology and research achievements of breast cancer.
出处 《生命科学》 CSCD 2007年第5期512-517,共6页 Chinese Bulletin of Life Sciences
基金 上海市公共卫生临床中心引进人才科研启动经费配套(RCJJP2)
关键词 乳腺癌 蛋白质组 激光捕获显微切割(LCM) 质谱 breast cancer proteomics laser capture microdissection(LCM) mass spectrometry
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  • 1Coldman A,Phillips N,Warren L,et al.Breast cancer mortality after screening mammography in British Columbia women.Int J Cancer,2007,120(5):1076-1080.
  • 2Rai A J,Stemmer P M,Zhang Z,et al.Analysis of Human Proteome Organization Plasma Proteome Project (HUPO PPP) reference specimens using surface enhanced laser des-orption/ionization-time of flight (SELDI-TOF) mass spectrometry:multi-institution correlation of spectra and identification of biomarkers.Proteomics,2005,5(13):3467-3474.
  • 3Somiari R I,Somiari S,Russell S,et al.Proteomics of breast carcinoma.J Chromatogr B,2005,815(1-2):215-225.
  • 4Celis J E,Moreira J M,Gromova I,et al.Towards discovery-driven translational research in breast cancer.FEES J,2005,272(1):2-15.
  • 5Posadas E M,Simpkins F,Liotta L A,et al.Proteomic analysis for the early detection and rational treatment of cancer realistic hope? Ann Oncol,2005,16(1):16-22.
  • 6Czerwenka K F,Manavi M,Hosmann J,et al.Comparative analysis of two-dimensional protein patterns in malignant and normal human breast tissue.Cancer Detect Prev,2001,25(3):268-279.
  • 7Cowherd S M,Espina V A,Petricoin E F 3rd,et al.Proteomic analysis of human breast cancer tissue with laser-capture microdissection and reverse-phase protein microarrays.Clin Breast Cancer,2004,5(5):385-392.
  • 8Zang L,Palmer Toy D,Hancock W S,et al.Proteomic analysis of ductal carcinoma of the breast using laser capture microdissection,LC-MS,and 16O/18O isotopic labeling.J Proteome Res,2004,3(3):604-612.
  • 9Fuller A P,Palmer-Toy D,Erlander M G,et al.Laser capture microdissection and advanced molecular analysis of human breast cancer.J Mammary Gland Biol Neoplasia,2003,8(3):335-345.
  • 10Espina V,Dettloff K A,Cowherd S,et al.Use of proteomic analysis to monitor responses to biological therapies.Exp Opin Biol Ther,2004,4(1):83-93.

同被引文献15

  • 1刘彦力,陈玉林,徐飞.开放实验网上预约系统的开发与应用[J].科技资讯,2008,6(20). 被引量:9
  • 2林冬梅,马莹,肖汀,郭素萍,韩迺珺,苏凯,易胜中,方健,程书钧,高燕宁.TPX2在肺鳞状细胞癌及其癌前病变中的表达和意义[J].中华病理学杂志,2006,35(9):540-544. 被引量:29
  • 3李英俊,孙淑琴,于世钧,安悦,张治广.多种模式开放实验室 培养创新人才的探索与实践[J].实验室研究与探索,2007,26(3):121-124. 被引量:164
  • 4Willert K,Brown J D,Danenberg E,et al.Writ proteins arelipid-modified and can act as stem cell growth factors[J].Nature,2003,423 (6938):448-452.
  • 5Ken M.Cadigan and Roel Nusse.Wnt signlaing:a common theme in animal development[J].Genes Dev,1997,11:3286-3305.
  • 6Miller JR.The Wnts[J].Genome Biol,2002,3001(3):123001-123015.
  • 7Willert K, Brown J D, Danenberg E, et al. Writ Proteins Arelipid-modified and Can Act as Stem Cell Growth Factors[J]. Nature, 2003, 423 (6938): 448-452.
  • 8K. Cadigan, R. Nusse, Genes Dev. 1997,11.
  • 9Miller JR. The Vents [J]. Genome Biol, 2002, 3(3001):123001-15.
  • 10Y. XIANG, D. S. NIE, G. X. L U. Cloning of a Novel Gene, Cymgl, Related to Family 2 Cystatins and Expressed at Specific Stages of Mouse Testis Development [J]. Acta Biochimica et Biophysica Sinica, 2005, 37(1): 11-18.

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