摘要
分析了加速器作为硼中子俘获治疗(BNCT)中子源的优势,提出以射频四极场(RFQ)加速器作为BNCT用中子源的首选机型。对该RFQ的参数进行了选择,利用质子轰击锂靶近阈反应产生的前冲中子束能散低、散角小的优势,设定RFQ最终能量为1.9 MeV。采用"匹配均温"设计方法进行了此强流质子RFQ的束流动力学设计,并对设计方案进行了传输模拟,在入口归一化均方根发射度为0.25 mm.mrad、流强为100 mA时,束流传输效率为99.3%。选择合适厚度的锂靶,经过整形即可得到满足BNCT治疗需要的中子束。
Boron neutron capture therapy（BNCT） is a promising approach for treatment of some malignant tumors, which can not be cured by conventional therapies, such as glioblastoma multiforme and melanoma. This paper mainly investigated the choice of the neutron source used for BNCT. Based on the analysis of the clinical requirements of BNCT and the characteristics of various neutron generators, the concept of using radiation frequency quadrupole（RFQ） as the preferred neutron source was brought forward. Since the epithermal neutron emits from the ^7Li（p, n）^7 Be near threshold reaction has low energy and small angular, 1.9 MeV was chosen as the final energy of the RFQ suitable for BNCT. In order to get enough neutron flux the induced proton current should be 100 mA. After choosing the basic parameters, the beam dynamic design study of the RFQ was carried out.
出处
《强激光与粒子束》
EI
CAS
CSCD
北大核心
2007年第10期1731-1734,共4页
High Power Laser and Particle Beams
基金
国家自然科学基金资助课题(10605003)
