Mayo评分与Child分级评估肝硬化患者预后

Comparison of Mayo Score with Child Score on Clinical Assessment in Patients with Liver Cirrhosis

目的:通过研究Mayo评分和Child分级与肝硬化患者预后的关系,比较两种方法预测肝硬化患者预后的价值。方法:回顾分析106例肝炎后肝硬化患者的临床资料,计算入院当天Mayo评分与Child分值,通过ROC曲线及截断值进行比较分析。结果:各组患者生存者与死亡者的Mayo评分与Child分值均有显著差异(P<0.05),3个月与2年生存期的患者两体系ROC曲线下面积有显著差异(P<0.05),而生存期1年的患者两体系ROC曲线下面积无显著差异(P>0.05)。结论:Mayo评分与Child分级均准确评估各生存期预后;Mayo评分适宜评估急、危重患者,而Child分级较适宜评估中长期患者。Mayo评分不仅适用于预测原发性胆汁性肝硬化患者预后,同样适用于肝炎后肝硬化患者。

Objective： To compare Mayo score and Child score on the evaluation of prognosis in patients with liver cirrhosis, after studying the relationship between Mayo score. Child score and the prognosis of those patients. Methods： The clinical data of 106 patients with liver cirrhosis caused by hepatitis were retrospectively studied, Mayo score and Child score on admission day were calculated and compared with reeeiver operating characteristic （ROC） curves. Results： Mayo score and Child score showed significantly difference （P〈0.05） between patients who survived and those who died. The ared under the ROC curves were significantly different （P〈0.05） between patients surviving for three months and those surviving for two years, while the ared under the ROC curves didn＇t have any obvious difference （P〉0. 05） among patients who survived for one year. Conclusion： Mayo score and Child score can accurately assess the prognosis of patients in different survival periods. Mayo score is used to patients in acute and critical periods, while Child score for patients of long-medium term. Mayo score can also assess the prognosis in patients with primary biliary cirrhosis and those with liver cirrhosis caused by hepatitis.