摘要
目的:评价乳腺癌肝转移介入治疗疗效,探讨其在乳腺癌肝转移综合治疗中的价值。方法:2000—2005年对68例乳腺癌肝转移患者共进行156次介入治疗,其中61例行超液化碘油栓塞。结果:应用世界卫生组织(WHO)实体瘤疗效评定标准评估治疗后疗效,68例中完全缓解(CR)0例(0%),部分缓解(PR)37例(54.41%),稳定(SD)26例(38.24%),进展(PD)5例(7.35%)。总客观有效率为54.41%。中位生存期为14个月,中位病灶稳定持续时间为9个月。6个月、l年、2年累积生存率分别为:92.60%、55.90%和17.00%。结论:乳腺癌肝转移的介入治疗疗效显著,毒副作用小,可以作为乳腺癌肝转移综合治疗中的主要治疗手段。
Objective: To analyze the efficiency of transhepatic arterial chemoembolization(TACE) for breast cancer patients with liver metastases (BCLM), evaluate its value among the serial therapy of BCLM. Methods: The data of clinical characteristics, response to treatment and survival were retrospectively analyzed in 68 breast cancer patients from 2000 to 2005 with liver metastasis using. Results: According to the world health orgnization(WHO) criterion, among the 68 patients 0 patients had complete response,37 patients (54.41%) had partial response,26 patients (38.24%) had stable diseases,5 patients (7. 35%) had progress diseases. The overall response rate of whole group was 54.41%. The median disease free survival and median time to survival of this series was 9 months, 14 months, the cumulative 6, 12,24 months survival rates were 92.60% ,55.90%, 17.00%, respectively. Conclusion.. Transhepatic arterial chemoembolization is a safe and effective therapy for liver metastasis from breast cancer. It should be the first line choice of treatment for breast cancer patients with liver metastasis.
出处
《中国临床医学》
北大核心
2007年第5期649-651,共3页
Chinese Journal of Clinical Medicine
关键词
乳腺癌
肝转移
介入
化疗栓塞
C臂计算机断层成像
Breast cancer
Liver metastasis
Interventional radiology
Transhepatic arterial chemoembolization
Dyna computed Tomography