Diver CE血栓抽吸装置在急诊冠状动脉介入治疗中的应用

The applying Diver CE thrombus-aspirating device in acute myocardial infarction

目的评价急性ST段抬高心肌梗死(STEMI)患者急诊冠状动脉介入治疗(PCI)中应用DiverCE血栓抽吸装置的效果与安全性。方法选择抚顺市中心医院2006年7月至2007年6月接受直接PCI的STEMI患者46例,分成血栓抽吸组与直接PCI组,比较两组间2h胸痛缓解率、ST段回落率、TIMI3级血流、肌酸磷酸激酶(CK)及其同功酶(CK-MB)峰值、左室射血分数(LVEF)及术后1个月内心脏不良事件发生率。结果血栓抽吸组的2h胸痛缓解率、ST段回落率、TIMI3级血流、CK及CK-MB峰值、LVEF值明显优于直接PCI组(P<0.05),术后1个月内心脏不良事件发生率两组差异无显著性意义(P>0.05)。结论PCI中应用DiverCE血栓抽吸装置能明显减少冠状动脉血栓及远端栓塞,有效地改善心肌灌注。

Objective To assess the effect and safety of applying Diver CE thrombus - aspirating device during direct percutaneous coronary intervention（PCI） in pations with ST- segment elevation myocardial infarction（STEMI）. Methods Select 46 patients with STEMI who underwent direct PCI between July,2006 and June,2007 in Fushun Central Hospital. Dividing these patients into thrombus- aspirating group and direct PCI group, comparing the difference in chest pain relieving, magnitude of ST - segment declining in 2h ,TIMI flow grade 3 ,the maximum value of CK and CK - MB ,EF and MACE outcome（death,myocardial infarction and targert vessel revascularization）. Results The percent of chest pain relieving,magnitude of ST- segment declining ,TIMI flow grade 3 ,the maximum value of CK and CK- MB, and EF in thrombus - aspirating group are piror to the direct PCI group （ P 〈 0. 05 ）. MACE outcome in one month is no statistical significance（P 〉0. 05）. Conclusion applying Diver CE thrombusaspirating device during PCI can obviously reduce thrombus in coronaty artery and distal embolization,improve myocardial reperfusion more effectively.