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基于抗体癌标志物研究 被引量:2

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摘要 癌细胞的产生是由于各种致癌因素引起基因调控失常,导致细胞癌变,并表达在正常情况下没有或含量甚低的蛋白和酶,这些癌性蛋白可能就是癌抗原,其分为癌特异性抗原和癌相关抗原,后者又分为癌分化抗原和癌胚抗原。细胞癌变时,细胞表面发生许多变化,其中糖类(碳水化合物)抗原最为明显。现发现细胞表面碳水化合物复合物中寡糖基本序列复杂,仅调节其形成的转移酶约有百余种,
作者 陈志南
机构地区 国家
出处 《国际免疫学杂志》 CAS 2007年第6期359-363,共5页 International Journal of Immunology
基金 国家"973"计划前期研究专项(2006CB70854)
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