含铜抗菌不锈钢的抗菌特性研究

STUDY ON ANTIBACTERIAL PROPERTIES OF COPPER-CONTAINING ANTIBACTERIAL STAINLESS STEELS

研究了铁素体和奥氏体含铜抗菌不锈钢的抗菌特性及相关机制.实验结果表明,含铜抗菌不锈钢具有优良的广谱杀菌作用,对本文选择的大部分革兰氏阴性菌(G^-)和革兰氏阳性菌(G^+)的杀灭率均在99.0%以上.通过铁素体抗菌不锈钢对大肠杆菌作用不同时间的研究证明,抗菌不锈钢的杀菌率和其与细菌作用时间有关,铁素体抗菌不锈钢与大肠杆菌作用150 min左右时间后的杀菌率才会达到99.9%的最大值.原子力显微镜的观察表明,抗菌不锈钢对大肠杆菌的杀灭表现为菌体内大量物质流失,细菌出现干瘪现象.电化学实验结果表明,抗菌不锈钢与大肠杆菌作用后,会由于其表面抗菌相中铜离子溶出的加快,而表现为其耐点蚀电位的下降.

The antibacterial properties and relevant mechanism of copper-containing ferritic and austenitic antibacterial stainless steels have been studied. Experimental results displayed that the copper-containing antibacterial stainless steels have the broad-spectrum antibacterial features, and the antibacterial rate against most of the Gram-negative bacteria and Gram-positive bacteria selected in the present work reached above 99.0%. Through studies on the different action times of E.coli in contact with ferritic antibacterial stainless steel, it was proved that the antibacterial rate of an antibacterial stainless steel should be related to the action time, and the antibacterial rate reached 99.9% only when the steel contacted with the bacteria for about 150 min. The AFM observation indicated that the antibacterial mechanism of the antibacterial stainless steels should be attributed to more leaking out of the materials and shriveling of the cells in the bacteria. The electrochemical experiments showed that after contacting with E.coli, the precipitation of Cu ions on the surface of antibacterial stainless steels became faster, resulting in a decrease of the pitting potential of the steel.