恶性梗阻性黄疸介入治疗常见问题的处理

Interventional radiology of malignant biliary obstruction complication and treatment

介入治疗作为恶性梗阻性黄疸的重要的治疗手段已经广泛应用,但仍有许多问题值得我们重视和研究。我们总结12年来800余例恶性梗阻性黄疸介入治疗病例的经验;详细分析恶性梗阻性黄疸介入治疗的适应证、禁忌证;研究介入治疗多种并发症的发生原因和处理方法;详细讨论胆管引流方法和胆管支架植入的时机和适应证;提出手术麻醉方法的选择、抗生素和止血药物的应用等见解;总结止痛剂的术前术后临床应用;对术后胰腺炎的发生和处理方法以及围手术期病死率进行了深入的探讨。希望我们的经验和教训能够对介入工作者有所帮助。

Intervetional therapy as an important therapeutic method for malignant biliary obstruction has been used extensively, but there still remain some problems worthy for our emphasis and research. We retrospectively reviewed more than 800 patients with malignant obstructive jaundice during 12 years. Indications, contraindications, complications and corresponding treatment methods were studied. Furthermore, discussion including methods of biliary drainage, proper time of stent implantation, methods of anesthesia, usage of antibiotics and haemostat were also carried out. Use of analgesics （pain-suppressal）preand post procedure, development of acute pancreatitis and its management, and peri-operative mortality were further investigated in detail. We hope our experiences and lessons would give interventional doctors some help in their career. （J Intervent Radiol, 2007, 16：649-551 ）