期刊文献+

VEGF-C用于胃癌诊断59例分析 被引量:1

下载PDF
导出
摘要 目的:研究VEGF-C在胃癌中表达及其与临床病理的关系,探讨VEGF-C与肿瘤转移的相关性。方法:采用免疫组化SP法,检测59例胃癌中VEGF-C表达情况,并计算微血管密度,采用SPSS软件进行统计学分析。结果:在淋巴结转移组VEGF-C的表达明显高于无淋巴结转移组(P<0.01),但在其他分组如年龄、肿瘤大小、微血管密度、组织学类型、血管浸润等VEGF-C表达均无相关性(P>0.05)。结论:VEGF-C的表达与胃癌的淋巴结转移有关。
出处 《中国误诊学杂志》 CAS 2007年第27期6631-6632,共2页 Chinese Journal of Misdiagnostics
  • 相关文献

参考文献5

  • 1Tang RF,Itakura J,A Kaw aT,et al. Overexpreession of lymphangiogenic growth factor VEGF-C in human pancreatic Cancer[J]. Pancreas, 2001,22 (3) : 285-292.
  • 2Jeltsch M ,Kaipainen A,Joukov V ,et al. Register for Free or Subscribe/Join AAAS to View Full Text [J]. Science, 1997, 276 (5317):1423-1425.
  • 3Yonemura Y,End Y, Fujita H,et al. Role of vascular endothelial growth factor 7 C expresson in the development of lymph node metastasis in gastric cancer[J]. Clin Cancer Res, 1999, 5(7): 1823-1829.
  • 4Jussila L, Alitalo K. Vascular gsowth factors and lymphangiogenesis [J]. Physiol Rev, 2002,82 (3) : 673-700.
  • 5Furudoi A,Tanaka S,Kitadai Y ,et al. Clinical significance of vascular endothelial groth factor C expression and angiogenesis at the deepest invasive site of advanced colorectal carcinoma[J]. Oneology,2002,62(2) : 157-166.

同被引文献17

  • 1甘海忠.VEGF在胃癌中的表达及意义[J].淮北职业技术学院学报,2008,7(3):36-37. 被引量:1
  • 2Weich HA, Bando H, Brokelmann M, et al. Quantification of vascular endothelial growth factor - C ( VEGF - C ) by a novel ELISA. J Immunol Methods ,2004,15,285,145 - 155.
  • 3Tamtra M, Ohta Y. Serumvascular endothelial growth factor - C level in patientswith primary monsmall cell lung carcinoma. A possible diagnostic ool for lymph node metastasis. Cancer, 2003,98 : 1217 - 1222.
  • 4Mitsuhashi A, Suzuka K, Yamazawa K, et al. Serum vascular endothelial rowth factor(VEGF) and VEGF -C levels as tumor markers in patients with cervical carcinoma. Cancer. 2005,15,103 : 724 - 730.
  • 5Duff SE, Li C, Renehan A, et al. Immunodetection and molecular forms of lasma vascular endothelial growth factor - C. Int J Oncol,2003,22:339 - 343.
  • 6Joukov V, Pajusola K, Kaipainen A, et al. A novel vascular endothelial growth factor, VEGF - C, is a ligand for the Fh - 4 ( VEGFR - 3 ) , and KDR( VEGFR - 2 ) receptor tyrosinc kinases [J]. EMBO J, 1996,15 (2) :290 -298.
  • 7YONEMURA Y, ENDO Y, FUJITA H, et al. Role of vascular endothelial growth factor C expression in the development of lymph node metastasis in gastric cancer[ J ]. Clin Cancer Res, 1999,5 : 1823 - 1829.
  • 8ICHIKURA T,TOMIMASTU S, OHKURA E, et al. Prognostic significance of the expression of vascular endothelial growth factor(VEGF) and VEGF - C in gastric carcinoma[ J]. J Surg Oncal,2001,78 : 132 - 137.
  • 9YANAI Y, FURUHATA T, KIMURA Y, et al. Vascular endothelial growth factor C promotes human gastric carcinoma lymph node metastasis in mice[ J]. J Exp Clin Cancer Res,2001,20(3 ) :419 -428.
  • 10YONEMURA Y, FUSHIDA S, BANDO E, et al. Lymphangiogenesis and vascular endothelial growth factor receptor(VEGFR) -3 in gastric cancer[ J ]. Eur Cancer,2001,37:918 - 923.

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部